Fermented organic soybean
Ferment 280 technology produces 280 types of natural beneficial bacteria that help balance the mouth and support the gut.
No-brush daily dental & oral care spray for dogs and cats
Ferment 280 technology produces 280 types of natural beneficial bacteria that help balance the mouth and support the gut.
Food-grade, high-pH water that unwelcome oral bacteria dislike — helping keep plaque and tartar in check.
Ionized alkaline water, beneficial bacteria blend derived from fermented organic soybean protein.
Gently lift your pet's lips and spray 2–3 times on each side, focusing on the back teeth and gums. Once a day.
Replace the cap after use. Store in a cool, dry place away from direct sunlight and humidity.


Customer photos. Individual results vary by pet.
Reviews from our customers, translated from Japanese. Individual results vary by pet.
My large dog pants heavily, and I'd started to notice bad breath, so I began using PROBIO mist as a trial. I spray it a few times a day. The breath has improved — and I was amazed to see the canine teeth turning whiter! I plan to keep going.
Our dog hates having teeth brushed, so we'd been getting tartar removed at the vet — which was an ordeal of its own. A friend told me about PROBIO mist, and now I give a quick spray after meals. Little by little, the yellowing is fading. Highly recommend!
Brushing was always refused, so dental care never really happened. I wanted to do something about recurring gingivitis, and that's how I found this spray. I love how easy it is — the gingivitis cleared up, and even the stains on the teeth came off. Completely satisfied.
The cat I rescued had badly damaged teeth and severe gingivitis, so I bought PROBIO mist. Lost teeth won't grow back, but I want to make the mouth as healthy as I can from here on. Since we started, the gingivitis has cleared up. The spray format makes it easy to use.
Such a welcome product for a dog who hates brushing. Ours has gotten so used to PROBIO mist that they open their mouth for it on their own — ha! The tartar is cleaning up nicely too. Truly happy with it!
It's incredibly easy to use — a quick spray, and my dog doesn't mind at all. It makes daily care easier, so I don't forget even on busy days.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.